The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess HRQL in patients with chronic . Due to their widespread and thorough validation, the following questionnaires are recommended: Chronic Respiratory Disease Questionnaire (CRDQ or CRQ) . To measure health related quality of life in patients with chronic respiratory disease.

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It has been used extensively in research and clinical trials since Combining scores from different patient reported outcome measures in meta-analyses: In the dyspnea and mastery domains, only one item was found to lack significant correlation over time. The original version of the CRQ was developed in by Guyatt et al 2 and followed Kirshner and Guyatt’s 7 principles of questionnaire development. A methodological framework for assessing rrespiratory indices.

Outcomes in Cardiopulmonary Physical Therapy: Chronic Respiratory Disease Questionnaire (CRQ)

Six minute walk test scores, however, were found to be only weakly correlated with all domains of the CRQ. Measuring patient and clinical perspectives to evaluate change in health-related quality of life among patients with chronic obstructive pulmonary disease. List per page or see all.

Also, in this specific patient population, improvements in rezpiratory or exercise tolerance may not be noticed since these patients are accustomed to avoiding activities that stimulate these symptoms. Because responsiveness might be of highest priority for some users of the CRQ, a version was developed that is self-administered but includes individualized dyspnea questions.

Williams et al 26 used standardized response means to assess the sensitivity and also found the CRQ-SR to be highly sensitive across all domains of the questionnaire indicating that it is able to detect changes following a treatment program. In order for a questionnaire to be considered practical, it must assess what it claims to measure.

There was good agreement between the predicted and actual correlations in both these cases. High reliability was found for the domains of dyspnea, mastery, and emotional functioning with scores as follows: The fact that correlations with physiologic measures are not strong suggests that HRQL instruments such as the CRQ may provide additional information that should be used alongside physiologic tests in determining the health status of a patient.


The total domain and the emotion domain scores were determined to be the most responsive to these changes. Eur Resp J Jan;25 1: This is most likely due to the fact that it includes domains of both physical and emotional health. Minimally clinically important difference MCID is a resource available to gauge if a patient deems intervention effective or not. A novel, short, and simple questionnaire to measure health-related quality of life in patients with chronic obstructive pulmonary disease.

Validity was determined to be strong; no statistically significant difference between the 2 instruments was found in the fatigue and mastery domains, and the small mean differences found in the dyspnea 0. Lower correlation scores were noted in the second 6 month period; however, they were not significant enough to indicate that bias existed between assessments. Construct validity refers to an instrument’s ability to measure the constructs, or abstract concepts, that it intends to measure.

Clinically important changes in health-related quality of life for patients with chronic obstructive pulmonary disease: Because under some circumstances investigators will want to use identical questions for ALL respondents the CRQ has been standardized through inclusion of five identical questions inquiring about dyspnea.

Measuring health related quality of life. It is known that mortality risk is not associated with the CRQ, 30 however, CRQ change scores associated with clinically important differences may be used to highlight significant changes in function and HRQL. National Center for Biotechnology InformationU.

With the development of the self-administered CRQ, validity of the newer instrument was established by comparing it to the gold standard of the original version. Pearson correlation coefficients were used to determine consistency over time of both individual item scores and domain total scores.

Puhan et al 12 used standardized response means SRMs to assess the responsiveness of the CRQ opposed to the t-test because it is independent of sample size. This validated and reliable tool is widely used to measure health related quality of life in patients with chronic airflow limitations. The CRQ is available in four different formats approximate time needed for the first administration:. This indicates that the CRQ was able to detect the change in patient condition that occurred with treatment.

ICCs of short term reliability ranged from 0.

Wyrwich et al 15 used triangulation methods to identify clinically important differences based on both patient and primary care provider PCP perceived differences. Patients were administered the Resoiratory before pulmonary rehab and again every 2 months after baseline.

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They administered the questionnaire 6 times in a 2-week interval to 25 patients with stable COPD.

Chronic Respiratory Disease Questionnaire (CRQ)

Prentice Hall Health; They found that mean scores were similar in all 4 respkratory over all administrations, and there did not appear to be a tendency for either improvement or decline.

According to the office of the developer, written communication, October, using the CRQ-IAS, in which the dyspnea section quuestionnaire also standardized, reduces the administration time to 8 minutes. All subsequent versions were developed in coordination with the original author, 78 and psychometric properties were evaluated and compared to the original CRQ. The conventional method of determining the MCID relies on the patient’s report reepiratory to the degree of change they have experienced in comparison to themselves; whereas, the method by Redelmeier et al 24 requires the patient to report the status of their condition in comparison to other patients with the same condition.

The limited availability of literature regarding intra-rater and inter-rater reliability indicates the need for further research in these areas. It has high internal consistency and test-retest reliability, as well as moderate to strong construct and convergent validity.

Outcomes in Cardiopulmonary Physical Therapy: Chronic Respiratory Disease Questionnaire (CRQ)

Twenty-eight patients with chronic lung disease received initial and follow-up questionnaires 2 weeks later after treatment had been initiated. These lower baseline scores and greater sensitivity of the self-report questionnaire can be attributed to the fact that patients are more likely to report the severity of the impairment when asked to fill out the questionnaire in private, as opposed to being asked by the interviewer. Cardiopulm Phys Ther J. Measuring functional status in chronic lung disease: The self-administered version may assist rspiratory the latter as it is associated with greatly decreased administration time.

It correlates well with other disease specific and generic measures of HRQL as well as with global ratings of change.